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Bobat H, Akyol M, Moradi P

Mitochondrial transplantation ameliorates the development and progression of osteoarthritis

Yes it is costly but, I found I was missing injections when I needed them due to getting myself worked up about doing it

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Some patients achieve lasting relief, while others may benefit from periodic maintenance injections

3.3 Risk assessment of bias in included studies Assessment of the 10 included trials using RoB 2.0 (Figure 2) revealed an overall risk of bias categorized as some concerns. Key methodological issues included inadequate randomization and allocation concealment, unclear blinding of outcome assessors, and potential selective reporting due to discrepancies between the registration protocol and the final published results