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In addition, cerebrovascular disease (stroke) and ischemic heart disease (IHD), both components of CVD, are expected to be the leading cause of death worldwide in 2030 (14)

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Mitochondrial damage may further amplify these effects through release of damage-associated molecular patterns (DAMPs) (80), which will reinforce chronic inflammatory signaling and contribute to the low-grade inflammatory state characteristic of immune aging

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Because these chemicals are produced when foods are being processed (typically with heat), they are known as process contaminants