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Early warning signs include persistent fatigue that does not improve with rest, difficulty concentrating or brain fog, tingling or numbness in hands and feet, weakness in the legs, dizziness when standing up, pale or yellowish skin, and a sore or swollen tongue

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In addition, the injected vessels are not compressed in rabbit ear vein studies, thereby resulting in the formation of a larger thrombus, which may allow for a more rapid or increased incidence of recanalization

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