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Furthermore, these models exhibit altered morphology, gene expression and have limited ability to replicate the complex immune responses such as interactions between macrophages, dendritic cells and T cells that occur in vivo ( in vitro models that can better replicate the in vivo tissue microenvironment

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The number of independent experiments is specified in the figure legends

According to Target Scans prediction, it has been suggested that there is a potential interaction between miR-485-3p and the 3-UTR sequence of FBXO45, indicating the possibility of binding between miR-485-3p and FBXO45s 3-UTR region

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