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Additionally, acetaldehyde affects histone acetylation, and its accumulation in excess amounts reduces ethanol-induced histone acetylation, possibly because it needs to be further metabolized (e.g., to acetic acid) [6]

Significantly reduced GPX4 levels in MCAO/R mouse or rat brains and in oxygen-glucose deprivation/reperfusion (OGD/R)-treated hippocampal neurons have the potential to exacerbate lipid peroxidation and ferroptosis

In contrast, we found that adding back cysteine to the MR diet reversed the chronic reduction of hepatic GSH by the diet and blocked its induction of FGF21 27

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doi: 10.1016/j.scienta.2020.109353

Foods like broccoli, cauliflower, Brussels sprouts, garlic, and onions are rich in sulfur, which supports glutathione production