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doi: 10.1111/jch.13583 139 MellBJalaVRMathewAVByunJWaghuldeHZhangYet al

Impairment of neutrophil chemotaxis and killing suggests that N0362 might bind to neutrophils

2.2.3 Physiological functions of microbial metabolites Gut microbial metabolites are important mediators connecting microorganisms and their host

Disclosures: Natasha Dilwali: Nothing to Disclose, Robin Howard: Mirum Pharmaceuticals: Stock - publicly traded company, Mirum Pharmaceuticals: Consultant, Mirum Pharmaceuticals: Employee, Mirum Pharmaceuticals: Consultant, Rachel Hallum-Montes: Mirum Pharmaceuticals: Independent Contractor, Yushan Kim: GRAIL: Employee, Mirum Pharmaceuticals: Consultant, Sherlock Biosciences: Consultant, Mammoth Biosciences: Consultant, Douglas Mogul: Nothing to Disclose, Wikrom Karnsakul: Nothing to Disclose 2471 CHILDREN WITH CHRONIC HEPATITIS C HAVE A HIGH PREVALENCE OF NEURODEVELOPMENTAL DISORDERS Shreya Kishore 1 Orlee Guttman 1 , 1 British Columbia Children's Hospital Background: Chronic hepatitis C (HCV) in children is primarily acquired through vertical transmission from an HCV-infected mother

This pattern was also observed in patients with treatment-resistant depression which sheds light on a very frustrating and frightening problem