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(1984) On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone

Protocol Overview: 10-Day Alternating Cycle Total Duration: 10 days (5 doses of each peptide) Schedule: Alternate peptides every other day (e.g., Day 1 MGF, Day 2 IGF-1 LR3, Day 3 MGF, etc.) Mechanism of Action MGF (Mechano Growth Factor): MGF is a splice variant of IGF-1 that is upregulated in muscle following mechanical overload or damage

Sustained elevation of IGF-1 is associated, in observational studies of acromegaly (a disease of GH excess), with increased risk of several cancers including colorectal and breast

Zhang, Y., Marcillat, O., Giulivi, C., Ernster, L

not clinically established

While preliminary findings paint an optimistic picture, robust and long-term studies are still required