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For instance, in vitro and in vivo studies using cancer cell lines (HT1080, HeLa, NCI-H1975 [human non-small cell lung cancer cell line], and B16F10 [human melanoma cell line]) demonstrated that combining ferroptosis activators with radiation therapy reduced tumor growth compared to radiation therapy alone [179,180,181,182]

Izco et al

J Chem Theory Comput 15:19831995

Thirdly, the exact mechanisms by which GSH-CDs exert their effects on IVDD might require more detailed investigation, including potential interactions with other cellular pathways

Overall, the results of this study are consistent with the above data on the elevated apoptotic activity in ASD that is tightly related to mitochondrial dysfunction [16]

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