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doi: 10.3390/nu14030614 [DOI] [PMC free article] [PubMed] [Google Scholar] 489

Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates

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This in turn leads to uncontrolled activation of the redox-sensitive, pro-inflammatory transcription factors NF-B, continued production of ROS and RNS and support of chronic inflammation

Acknowledgements The authors would like to thank all colleagues and institutions who provided support and valuable insights during the preparation of this review