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At that time, interest in KD for the treatment of this disease decreased and did not come to peoples attention again until the 1990s (2, 3), when its therapeutic effects were gradually found to be effective in a wide range of diseases and more therapeutic potentials of KD were proposed

This ethical approval and consent process ensured that the study adhered to established guidelines for protecting human participants in research

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Thanks to this work, we confirmed the reliability of cortical neuron culture as a valid SMA in vitro model for screening therapeutic treatments and we demonstrated the potential of 10H-PTZ for drug repurposing for SMA